Saturday 26 April 2014

What is methylisothiazolinone (MI ) - and why should we find out ?


What is methylisothiazolinone (MI ) - and why should we find out ?

Methylisothiazolinone (MI ) is a chemical preservative found in many common skincare products including liquid soaps, moisturisers, make-up , baby wipes and sunscreens and also more widely in paints, laundry products and even in paper used for wrapping food.
There have been concerns about it as  an  allergen in the UK press since 2013 .
It was named "Contact Allergen of the Year 2013" by the American Contact Dermatitis Society.
Allergy to MI manifests itself in different ways, from an obvious  red, raised itchy rash which may blister to a longer term contact dermatitis/eczematous reaction where the skin is chronically red and irritated. 
The most commonly affected areas are the face following use of liquid soaps and shampoos, hands and the buttocks and genital areas from use of pre moistened wipes, such as  when changing baby’s nappies or after using the bathroom . It may even be the person who changes the nappies who has the allergy, not the baby!
For example, in the event that an allergy to MI is suspected  Dr Zirwas says “If someone suspects an allergy to moistened wipes, they need to stop using them for at least one month. A week or two isn’t enough time. ”
MI is so widely present that it is really important for the consumer to be aware of it when they make a purchase. 
It is important to note that the majority of the population are not sensitive to this chemical but if you suspect that it may at the root of your problems, or if you wish to avoid it, you do need to become an “allergen-detective ” making the effort to check for Methylisothiazolinone , usually at or near the end of the ingredients listing when you are making a purchase.
Wash Products Containing MI :
MI is present in so many wash products that it is unrealistic  to think of compiling a comprehensive  listing but we have given pointers to some of the most popular ranges in which it is found, some of which were quite surprising . 
Shampoos containing MI :
It is almost impossible to avoid MI when it comes to shampoos but  a look around the shelves in Boots turned up the following which do not contain MI: L'Oreal, Schwarzkopf, Dr Wolf, Garnier and Trevor Sorbie are all MI – free as far as I could see, and Johnson and Johnson’s Baby Shampoo is  also MI-free. 
Nonetheless, it is very important to check for yourself as, since this information became available last year, many companies have been making a big effort to eliminate MI from their ranges and things are changing fast. 
With regard to baby wipes many wipes are now manufactured without MI and it is possible to get a 100% natural option but do check the packaging before buying.

Found on a recent shopping trip :  
All the following companies have skincare/hand/bodywash products which contain MI , so do look at the labels if you are considering a purchase and want to avoid it.
Baylis and Harding
Boots own brand
Champneys
Cussons Baby range
Clarins
Clinique
Dettol
Disney Princess
Dove
FCUK
Imperial Leather
Marks and Spencer
Sanctuary Spa
Soap and Glory
Ted Baker
Tesco own brand
TOPMAN
Treacle Moon
This is not an exhaustive list, merely products on the shelves on an ordinary day and there are many others  which I could not track down, I am sure. Nonetheless it is an illustration of how hard it is to avoid MI when you are shopping for your skincare . 
It is likely that long term most companies will remove this chemical from their products, but it may take some time and in the meantime those of us who are concerned need to take the initiative and do our own homework.

Background information :

The chemical preservative methylisothiazolinone, (used to prevent bacterial growth in water-containing commercial cleaning products) also known as MI , was previously mixed with another preservative, Methylchloroisothiazolinone (MCI) in a three-to-one ratio ( as it still is in the USA )  in a product called Kathon CG. (They are still commonly found together in skincare products but not in this single product in the EU.)

However in the EU, growing concerns in the mid-2000s about MCI causing allergies meant some manufacturers started using MI as a single agent but at a much higher concentration than before.
When the two compounds were used, MI it was found in concentrations of around four parts per million (ppm). On its own a level of up to 100ppm, a 25-fold increase, is allowed under European regulations introduced in 2005.

Experts believe there is a link between the serious rise in cases of contact dermatitis and the increase in its concentration in skincare products  particularly in the last two years. While a 1 -2% rate of allergy to any product might be expected, the rate of allergy to MI can be 10%.

In January 2013  Margarida Gonçalo, the president of the European Society of Contact Dermatitis (ESCD,  wrote to the European Commission calling for an investigation into what levels of MI are safe.
She said: “This new epidemic of allergic contact dermatitis from isothiazolinones is causing harm to European citizens; urgent action is required.”

In July 2013 Dr John McFadden, consultant dermatologist at St John’s Institute of Dermatology in London said about MI,  “We are in the midst of an outbreak of allergy to a preservative which we have not seen before in terms of scale in our lifetime. Many of our patients have suffered acute dermatitis with redness and swelling of the face. I would ask the cosmetics industry not to wait for legislation but to get on and address the problem before the situation gets worse.”

This is not a new scenario, methyl­dibromo glutaronitrile, another preservative, was banned from use in cosmetics in 2005 after it was linked to an increase in eczema cases.

However, experts believe that the increase in eczema cases is happening even faster with MI and some specialists have been even more outspoken : Consultant dermatologist  Dr Ian White, has been reported as saying : “Bluntly, I think the European Commission has been negligent over this, they have had warning after warning. If it was food there would have been action.”

In his  response at that time Dr Chris Flower, director general of the Cosmetic, Toiletry and Perfumery Association, the UK cosmetic trade association, said : “Human safety is the cosmetic industry’s number one priority; in fact it is the law. Every cosmetic product must undergo a rigorous safety assessment before it is placed on the market. The assessment covers all of the ingredients, the final product, how and where the product is to be used, how often and by whom and must be carried out by qualified assessors.”

On 12th December 2013  Cosmetics Europe, the personal care association, issued an industry-wide recommendation to discontinue the use of the preservative MI  in leave-on skin cosmetics and personal care products.  The recommendation was made in the interests of consumer health and in response to recent clinical data showing an increase in adverse skin reactions to MI.

Until 2013 the worries about MI focused on its presence in “leave-on” products , those products which are designed to remain on the skin such as as creams or lotions .
However in the US, the director of the contact dermatitis center at Ohio State University’s  Wexner Medical Center, Dr Matthew Zirwas has identified MI as being linked to a dramatic rise in allergic reactions in other common skincare products as well .
 Dr Zirwas says : “In the last two or three years, we’ve suddenly seen a big increase in people with this type of allergy. For some patients, their rash has been unexplained and going on for years.”
MI is found in many water-based products like liquid soaps, hair products, sunscreen, cosmetics, laundry products and cleaners as well as pre-moistened personal hygiene products and baby wipes.
The irony is that many people are developing these reactions to products which they are using to clean themselves and in our modern search for total hygiene may even inadvertently increase their use in the mistaken belief that they may be able to help them clear up the very allergy they are causing!

Disclaimer : This blog represents my own views and are not intended as medical advice. If you have any concerns about skin/health problems , please contact your own doctor who will be able to advise you .

Friday 18 April 2014

What’s Really In Your Skin Care Products?

Many people are concerned about the skin care products they use : they read all the reports about allergies and dermatitis or maybe they want to avoid added preservatives or fragrances.
It can be hard to keep up to speed with all the options out there and sometimes it is difficult to recognise all the ingredients on the list!

Once a week I will be taking a topic and looking into it to provide an interesting snapshot of some of the live issues in skin care. It may be an individual company, an overview of a product area  or  a specific ingredient.
This week I will be putting the preservative methylisothiazolinone (MI ) under the microscope.
What is it, what does it do and where is it found?  Watch this space to find out!